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The And Clinicopathological Value Of Poly ( Adenosine...

Prognostic and Clinicopathological Value of Poly (Adenosine Diphosphate-Ribose) Polymerase Expression in Breast Cancer: A Meta-Analysis Weiqiang Qiao Ming Yang* Department of Breast Surgery, First Hospital of Jilin University, Changchun, China * Corresponding author Ming Yang, MD Address: Tell: Fax: E-mail: yangming.1967@163.com Abstract Background: Previous researches have shown that poly (adenosine diphosphate-ribose) polymerase (PARP) level was a promising predictor for breast cancer. However, its prognostic value remains controversial. The present meta-analysis evaluated the prognostic value of PARP expression in breast cancer. Materials and methods: Eligible studies were retrieved in PubMed, Web of Science, Embase, and the Cochrane Library databases until July 20, 2016. Studies investigating PARP expression as well as reporting survival data in breast cancer were enrolled. Two independent reviewers carried out all the literature searches. The pooled relative risk (RR) and hazard ratio (HR) with 95% confidence interval (95% CI) were applied to assess the association between PARP level and the clinicopathological features and survival outcome in breast cancer. Results: A total of 3506 patients from eight eligible studies were included. We found that higher PARP expression indicated worse clinical outcome in early stage breast cancer, with an HR of 3.07 (95% CI, 1.14-8.29, P = 0.027) for disease-free survival (DFS) and an HR of 1.65

Human Resource Management for Diversity -myassignmenthelp.com

Question: Discuss about theHuman Resource Management for Diversity. Answer: Diversity Diversity is related to acknowledging, accepting and understanding the differences that are seen among the people with respect to age, class, race, gender. It is evaluated that every individual has some visible and non-visible changes and by giving value to the differences the individual feel valued for the struggles that are not only valuable for the person but also for the organization. By taking into consideration the word diversity, the emphasis is given to the groups that consist of the qualities of an individual that are diverse from the behavior. To give value to the diversity at the workplace is essential nowadays. To give value means to create an environment that maximizes the potential of the employees in which every individual feels that they are a part of the team. By giving value to diversity in the organization means that the acknowledgment is given to other culture and races that have equality (Barak, 2016). Diversity in the organization means that the candidates are employed without any discrimination that is related to the gender, age, religious belief and the cultural background of the people. It is also related to the education level, experience in life, social and economic background. The experience of work and also marital status are included in diversity. If the diversity is concerned with the workplace, then it means to find the values of various individuals and also to manage the environment in an effective manner (Trax, Brunow Suedekum, 2015). To manage the diversity it is essential to make those surroundings that can give the full contribution of people belonging from different backgrounds. So it is evaluated that the main focus of the organization is on implementing the strategies that consist of different responsibilities of the employees and also on the different background. It takes into consideration all the contribution that diversity has given focus so that the new ideas can be generated and also the techniques can be taken into consideration to conduct the operations of the business. Diversity considers all the policies that are concerned with the equal employment opportunity that is essential for the workplace. A diverse business is one that considers the values that make the difference in the individual. The organization that is diverse gives encouragement and also considers the differences that are possessed so that their services can be relevant and easy to approach (Leng Yazdanifard, 2014). The organizations that are diverse take into consideration various views and experiences so that the needs of the individual can listen in a proper way. If the encouragement takes places then it gives direct impact on the society. In today scenario, many people take the diversity of good things because it offers the people various opportunities to experience various things that are not experienced in a normal course of a period (Harvey Allard, 2015). Diversity is related to the tricky things and also it helps to understand both the negative and positive effects on the society like on education and employment. The individual has to search a lot to find out what exactly the effect will be in the end and also it helps to be patient to see the outcome. There are various advantages that are related to the diversity in the workplace. It enhances the opportunities for marketing, recruitment and also on the image of the organization. If the organization give focus on the outcome and do not give focus on the diverse team, then it is analyzed that the communication and trust can be broken and the performance level goes down. Also, there are various limitations that are related to diversity (Meyers Vallas, 2016). The negative behavior can create hindrances to the organizational diversity. It is because it damages the relationships and also reduces the level of productivity and morale. The diversity in the workplace enhances the opportuniti es for the business to attain a perspective in the situations and also helps to improve the global reach but it does not give negative impact on the company operations. The principles of the diversity in the workplace should be considered and it gives emphasis on the human resource management. It is essential that the organization should show the high level of commitment level towards diversity and should have a flexible working condition that assists the employees to balance their work and also the responsibilities of the organization (Adams Bell, 2016). The strategies of diversity in the workplaces assist the organization to enhance the relationships with the community and also to increase the contribution level of the employees. The quality of the programs, products, and services delivered are also increased in an efficient way. The organization that aims to attain the success gives focus on the main principles of diversity to be implemented in their cultures and management system. The principle of diversity enhances the value of the organization. The change in people management can be easily seen and it gives the positive impact on the working operations of the company. There are various benefits that are related to the workplace diversity. One advantage is that it enhances the adaptability of the company. The solutions can be given to every problem just by giving employment to the diverse employees in an organization. The employers who are from a diverse background not disclose the talent of the individuals but also gives ideas t hat are innovative and can help to adapt the demand of the customers and the fluctuation of the market (Chrobot-Mason Aramovich, 2013). Diversity also helps to offer globalization. It has a collection of the workforce in a company that gives the diverse collection of the skills and also allows the company to offer services to the customers globally. The diverse employee also has the comfort level that helps to communicate at many points and also gives innovative ideas and experience. The company can take into consideration those ideas that can meet the strategy of business needs. The needs and wants of the consumers are also meet effectively. So, if the organization has diverse employees then it can bring high values. To give respect to all the employees of the organization can give an advantage that creates a competitive edge and also enhances the productivity level (Guillaume, Dawson, Otaye?Ebede, Woods West, 2017). References Adams, M., Bell, L. A. (Eds.). (2016).Teaching for diversity and social justice. Routledge. Barak, M. E. M. (2016).Managing diversity: Toward a globally inclusive workplace. Sage Publications. Chrobot-Mason, D., Aramovich, N. P. (2013). The psychological benefits of creating an affirming climate for workplace diversity.Group Organization Management,38(6), 659-689. Guillaume, Y. R., Dawson, J. F., Otaye?Ebede, L., Woods, S. A., West, M. A. (2017). Harnessing demographic differences in organizations: What moderates the effects of workplace diversity?.Journal of Organizational Behavior,38(2), 276-303. Harvey, C. P., Allard, M. (2015).Understanding and managing diversity: Readings, cases, and exercises. Pearson. Leng, C. Z., Yazdanifard, R. (2014). The relationship between cultural diversity and workplace bullying in multinational enterprises.Global Journal of Management And Business Research. Meyers, J. S., Vallas, S. P. (2016). Diversity Regimes in Worker Cooperatives: Workplace Inequality under Conditions of Worker Control.The Sociological Quarterly,57(1), 98-128. Trax, M., Brunow, S., Suedekum, J. (2015). Cultural diversity and plant-level productivity.Regional Science and Urban Economics,53, 85-96.

Sell Your Own Merchandise With Print-on-Demand on WordPress Beginners Guide

The topic of website monetization is one of the most common and also one of the more mysterious ones out there. Weve been talking a lot about monetization in other places, and there are lots of methods to make your time worthwhile with a site. However, how about looking into something that might not be that obvious at first? This is where custom merchandise comes into play and the idea of print-on-demand on WordPress.In other words, how about offering your audience some custom-made mugs, t-shirts, and all sorts of other things? Lets welcome Fionn Concannon whos going to tell us all about how its done. Artists and creative craftspeople also benefit from this development. The print-on-demand model opens many possibilities to start a new business and sell their creations. If you operate in the creative field and start a new venture, all you need is to build a simple WordPress website, put WooCommerce on top of it, and promote your online store through digital channels. You can sell your own custom merchandise, without the associated risksPlatforms you can use for the print on demand modelSetting up a e-commerce shop with PoD might seem a daunting task, especially if you are not tech-savvy. However, there are many resources available to guide you through the process to start an online store with WordPress. Furthermore, you dont need lots of investment to start it nor an inventory, nor a physical space.The first thing you need is to choose a platform to integrate into WordPress to host your shop. Depending on your skills, some will work better than others. For example, if you are a beginner its better to choose a platform with an easy-to-use interface, but if you are more experienced youll probably need a platform that allows more customization to adapt it to your specific needs.First, lets take care of the elephant in the room. No one is forcing you to use WooCommerce. It is one of the options, yes, but its not a must. You can safely use other platforms and only i ntegrate them with your WordPress setup on the surface.Heres a summary of the  three of the most popular e-commerce platforms that you can use:ShopifyThis platform is very straightforward and easy to use. Just choose one of the plans, link your domain to your Shopify account, set your design / template, add your products and payment options. Thats it! Your shop is ready to be discovered.Adelina Tuca recently listed the 20+ best Shopify themes, which is definitely worth a read.To integrate your catalogue for PoD, you simply have to select the most appropriate Shopify app, and install it.Shopify is an all-round service which also provides security for financial transactions, solid customer service, assistance with marketing and design, and a selection of add-ons to customize e-commerce shops. This platform has been at the forefront of custom merchandise e-commerce, and continues to attract entrepreneurs from many different industries.When you have everything set up at Shopify, you c an take embed codes for the buy buttons, and place them throughout your WordPress website, for a smooth integration.Magento Magento is an open source e-commerce solution. It is one of the most popular platforms on the market, due to its flexibility. Magento offers a community version which is free, plus some paid-for options as well. It can be integrated into your WordPress website with a plugin and, for your PoD service you will need to install one of their extensions.The main advantage of using Magento is that it has many features, an intuitive interface, and flexibility to customize every aspect. It has a community of users that are continuously creating new extensions, and there is plenty of support on offer. However, the price does rise if you need a more complex service, and often it can be difficult to find good developers when required.Overall, this is an option for the more advanced user who needs very specific features and probably operates at a higher volume.WooCommerceWo oCommerce is one of the most powerful platforms for e-commerce.WooCommerce is an open-source e-commerce plugin for WordPress and now one of the most popular e-commerce solutions on the web.It offers a good user experience, and the basic functions are free.WooCommerce is a great platform for e-commerce startups, especially if youre already using WordPress. It also has integration for print-on-demand and drop-shipping services.There are many options to customize your shop with WooCommerce extensions. This platform is also easy to learn, especially if you are already familiar with WordPress. It is very popular, which means that there are lots of community support on offer when required.Having hard time to decide? Heres some further reading:WooCommerce vs Magento which is better?Shopify vs WooCommerce which is better?Who uses print on demand as a business model?Creatives and design professionalsCustom merchandise is a fantastic opportunity for creatives to monetize their work. PoD is on the rise, providing an excellent opportunity for artists, photographers, designers and all creative people to become entrepreneurs and sell their craft online, without the physical hassle.Artists can create their designs as usual, using tools like Adobe Illustrator, InDesign or Photoshop. Thereafter, they can upload a high-quality image to their chosen platform and the PoD service does the rest. The product will be printed and shipped directly to the customer.Art can be sold as the usual prints, but you can also have it on canvas, phone cases, t-shirts, duvets, cushions, etc. Furthermore, it is not necessary to have a big stock as these products are created only after the customer has paid for them.Businesses and SMEsGone are the days when businesses and SMEs had to order large quantities of merchandise and deal with any unwanted or unused items. Even worse was discovering a mistake after a huge order had arrived and been paid for. This could cripple businesses unexpectedly.On-de mand printing is a low-risk option for any business. For example, delivery costs are minimized and its usually the customer who pays. Warehouse costs are also reduced, as you dont need to keep any inventory. In this sense, disposal of unwanted items costs is also eradicated as you can control the amount you order. Updates and changes are usually free of charge, and there is usually a fast turnaround for production.The additional benefit is to have a vast product range, containing unique branded merchandise. In a world that has become more homogenized, SMEs and small e-commerce stores can set themselves apart with custom designs which are not available anywhere else in the world.Without innovative technology, this wouldnt have been possible.Promoting your store and custom merchandiseSo, you now have your store up-and-running, and you have created some fantastic merchandise to sell. But now you need to promote your e-commerce business and its products, and reach a wide audience.The pl atforms discussed earlier will offer marketing advice and tools, but you will need to have a good strategy in place to stand out from the crowd and succeed in a competitive market. Here are the top 4 channels for effective promotion of your custom merchandise store.SEO PPCYou will need to optimize your site so it can be found by the search engines. This is one of the best long-term methods to drive traffic to your website and increase sales. First and foremost, your WordPress site must adhere to Googles own guidelines. Free tools such as Yoast are perfect for managing SEO on your WordPress e-commerce store.SEO is a wide-ranging and complex practice, involving on-site optimization and other tactics such as link-building and content expansion. You can follow this comprehensive guide from Kissmetrics to improve your e-commerce SEO. SEO requires a lot of hard work and patience, and this practical guide by Alex  is perfect for those who arent keen on the process.PPC is a more immediat e route to market. The most popular platform for PPC is Google AdWords. These are text-based ads placed in the search results, or display ads placed across Googles network. You can tailor campaigns to your niche, and get extremely granular with targeting across multiple ad sets. The Sleeknote guide to AdWords for e-commerce  is worth a read to understand the essentials.Content marketingContent is king. You should create content for your audience, tapping into their needs, wants, interests, and concerns. A blog is a good first step, although content marketing doesnt stop here. You can read this fantastic introduction to content strategy for in-depth guidance.Essentially, you need to plan whether your content meets certain stages of the buyer journey, plus team up with influencers to expand reach, and incorporate sponsored promotion to get more eyeballs on the best content.User-generated content is great, and reviews or testimonials still have an essential place in the content marke ting mix. Written content is effective, but consider different media, from video to audio. Team up with partners to collaborate on content projects.Social mediaThere are billions of people using social media every day, and your customers are likely to be using it too. Social media is a great channel to disseminate content that you have created, to build a community of followers, and to boost your direct sales. You will need to identify where your customers are, and target them carefully with pertinent content.You have the option of focusing on Facebook, Instagram, Twitter, Pinterest, LinkedIn, and many other platforms on the web. You can embark on organic campaigns, or invest budget in adverts and sponsored posts. The social world is your oyster!SummaryWhen technology and creativity combine, new business opportunities arise. This is the case of print-on-demand, which elevates the e-commerce model to new heights. The creative industries now have control and ultimate flexibility, and small businesses no longer need to invest risky amounts in stock prior to sale. The model works for all involved.The ability to produce and sell custom merchandise means that every WordPress e-commerce store can offer a unique product range at any time. Customers are no longer limited to buying big brand products, and entrepreneurs have a solid opportunity to reach people all around the world via digital channels. About the author:  Fionn Concannon is the Co-Founder and Managing Director at KITE your place to go for print-on-demand solutions re-imagined.